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Chlorodifluoroethane (HCFC)

Chlorodifluoroethane is a liquefied gas and exists as a liquid at room temperature when contained under its own vapor pressure, or as a gas when exposed to room temperature and atmospheric pressure. The liquid is practically odorless and colorless. Chlorodifluoroethane is noncorrosive and nonirritating.
is a liquefied gas and exists as a liquid at room temperature


1, 1-Difluoro-1-chloroethane; Dymel 142b; Genetron 142b; HCFC
142b; P-142b; propellant 142b; refrigerant 142b; Solkane 142b.

Chemical Name and CAS Registry Number: 1-Chloro-1, 1-difluoroethane [75-68-3]

Empirical Formula and Molecular Weight: C2H3ClF2 100.50

Functional Category: Aerosol propellant.

Applications in Pharmaceutical Formulation or Technology

Chlorodifluoroethane is a hydrochlorofluorocarbon (HCFC) aerosol propellant previously used in topical pharmaceutical formulations. However, it is no longer permitted for use in pharmaceutical formulations because of its harmful effects on the environment. It was also generally used in conjunction with difluoroethane to form a propellant blend with a specific gravity of 1. Chlorodifluoroethane was also used in combination with chlorodifluoromethane and hydrocarbon propellants. Chlorodifluoroethane may be used as a vehicle for dispersions and emulsions.

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