Chlorocresol - Gafacom (For health. For knowledge)

Chlorocresol


Colorless or almost colorless, dimorphous crystals or crystalline powder with a characteristic phenolic odor.

Nonproprietary Names

  • BP: Chlorocresol
  • PhEur: Chlorocresol
  • USP-NF: Chlorocresol
Colorless or almost colorless, dimorphous crystals or crystalline powder with a characteristic phenolic odor


Synonyms

Aptal; Baktol; chlorocresolum; 4-chloro-m-cresol; p-chloro-mcresol; 1-chloro-4-hydroxy-2-methylbenzene; 2-chloro-5-hydroxytoluene; 6-chloro-3-hydroxytoluene; 4-chloro-3-methylphenol; 3- methyl-4-chlorophenol; Nipacide PC; parachlorometacresol; PCMC.




Chemical Name and CAS Registry Number: 4-Chloro-3-methylphenol [59-50-7]

Empirical Formula and Molecular Weight: C7H7ClO 142.58

Functional Category: Antimicrobial preservative; disinfectant.

Applications in Pharmaceutical Formulation or Technology

Chlorocresol is used as an antimicrobial preservative in cosmetics and pharmaceutical formulations. It is generally used in concentrations up to 0.2% in a variety of preparations except those intended for oral administration or that contact mucous membrane.
Chlorocresol is effective against bacteria, spores, molds, and yeasts; it is most active in acidic media. Preservative efficacy may be reduced in the presence of some other excipients, particularly nonionic surfactants. In higher concentrations, chlorocresol is an effective disinfectant.



Chlorocresol Chlorocresol Reviewed by gafacom on April 01, 2020 Rating: 5

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