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PREGABALIN (25Mg/50Mg/75Mg/150Mg/300Mg capsules)

gafacom - pregabalin

Active substance: Lactose anhydrous USP, Pregelatinized starch USP, Talc USP.

ü  Management of neuropathic pain associated with diabetic peripheral neuropathy

ü  Management of post herpetic neuralgia
ü  Adjunctive therapy for adult patients with partial onset seizures
ü  Management of fibromyalgia

Pregabalin is contraindicated to known hypersensitivity to pregabalin or any of its components. Angioedema and hypersensitivity reactions have occurred in patients receiving pregabalin therapy.

           Pregabalin is given orally with or without food. The maximum recommended dose of pregabalin is 100mg three times.

ü  Angioedema- can cause angioedema
ü  Hypersensitivity- skin redness, blisters, hives, rash, dyspnea and wheezing.
ü  withdrawal of Antiepileptic Drugs( AEDs)
As with all AEDs, withdraw pregabalin gradually to minimize the potential of increased seizure frequency in patients with seizure disorder.
ü  Suicidal Behavior and ideation- Antiepileptic drugs(AEDs) including pregabalin increase the risk of suicidal thoughts
ü  Peripheral edema- can cause peripheral edema
ü  Dizziness and Somnolence
ü  Weight gain- can cause weight gain
ü  Decreased platelet count – can lead to decreased blood platelet

ü  Dizziness and Somnolence
ü  Headache
ü  Ataxia
ü  Asthenia
ü  Dry mouth
ü  Constipation
ü  Edema
ü  Blurred vision
ü  Weight gain
ü  Thinking abnormally
ü  Keep out of reach of children
ü  \protect from light and mixture
ü  Store below 30°c in dry place


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